Market Outlook
The Nitinol-Based Medical Device Market was valued at USD 4.86 Billion in 2025 and is projected to grow to USD 8.74 Billion by 2033, with a compound annual growth rate (CAGR) of 7.6% from 2027 to 2033. The global Nitinol-based medical device market is witnessing consistent growth, supported by the increasing integration of advanced biomaterials in modern healthcare systems. Nitinol, an alloy of nickel and titanium, is valued for its unique properties such as shape memory and superelasticity. These characteristics enable medical devices to return to their original shape after deformation, making them highly suitable for minimally invasive procedures. As a result, Nitinol is widely used in applications such as cardiovascular stents, guidewires, dental instruments, and orthopedic implants.
One of the primary drivers of this market is the rising prevalence of chronic diseases, particularly cardiovascular and musculoskeletal disorders. The growing aging population globally further contributes to demand, as older individuals often require implantable and long-term therapeutic devices.
In addition, the healthcare industry’s shift toward minimally invasive procedures has significantly increased the adoption of Nitinol-based devices, as they offer reduced recovery time, lower risk of complications, and improved patient comfort.
Technological advancements are also playing a crucial role in market expansion. Continuous improvements in manufacturing processes, including precision laser cutting and surface modification techniques, have enhanced device performance, durability, and safety. Furthermore, increased investment in research and development is enabling the creation of more complex and application-specific devices, broadening the scope of Nitinol across various medical specialties.
However, the market faces notable challenges. High material and production costs remain a key barrier, especially in price-sensitive regions. The manufacturing process of Nitinol devices is complex and requires strict quality control, which increases operational costs. Additionally, stringent regulatory requirements and lengthy approval processes can delay product launches.
Another concern is related to biocompatibility and potential nickel sensitivity in some patients, which may limit usage in certain cases. Moreover, competition from alternative materials and conventional devices continues to pose challenges to widespread adoption.
Pricing & Cost Analysis
The pricing and cost structure of the global Nitinol-based medical device market is primarily driven by the high cost of raw materials, complex processing, and stringent regulatory requirements. Nitinol alloy prices typically range from around $150 to $400 per kg for standard grades, while advanced medical-grade or customized forms can reach $800 to $2,000 per kg depending on purity, specifications, and volume . These material costs significantly influence overall device pricing.
Manufacturing costs are further elevated by the need for precision engineering, including laser cutting, shape-setting heat treatments, and surface finishing to ensure optimal performance. These processes are essential to maintain the alloy’s unique shape memory and superelastic properties. In addition, biocompatibility testing, sterilization, and adherence to global medical regulations increase production costs substantially.
Overall, raw material and processing expenses form a major share of total device cost. As a result, Nitinol-based devices such as stents and guidewires are priced at a premium. High research, development, and quality assurance investments further contribute to the overall cost burden.
Market Dynamics
Rising prevalence of cardiovascular diseases is increasing demand for minimally invasive devices made with Nitinol.
The rising prevalence of cardiovascular diseases (CVDs), including conditions such as coronary artery disease, arrhythmias, and peripheral vascular disorders, is a major factor driving the demand for Nitinol-based medical devices. Sedentary lifestyles, unhealthy dietary habits, increasing obesity rates, and aging populations are significantly contributing to the global burden of heart-related ailments. As a result, there is a growing need for effective, safe, and less invasive treatment options.
Minimally invasive procedures have gained strong preference over traditional open surgeries due to their advantages, such as reduced recovery time, lower risk of complications, shorter hospital stays, and improved patient outcomes. Nitinol, with its unique properties like shape memory and superelasticity, plays a crucial role in enabling these advanced procedures. It is widely used in devices such as stents, guidewires, and catheters, which can navigate complex vascular structures with precision and flexibility.
Additionally, healthcare providers and patients are increasingly opting for treatments that offer quicker recovery and lower overall healthcare costs. This shift is further accelerating the adoption of Nitinol-based devices, making them essential in modern cardiovascular interventions and supporting the overall growth of the market.
High manufacturing costs and complex processing of Nitinol limit its widespread adoption.
High manufacturing costs and the complex processing requirements of Nitinol significantly limit its widespread adoption in the medical device industry. Nitinol, an alloy of nickel and titanium, requires precise composition control and highly specialized production techniques to achieve its unique properties, such as shape memory and superelasticity.
Even slight variations in temperature, composition, or processing conditions can impact its performance, making manufacturing highly sensitive and technically demanding.
The production process involves multiple stages, including vacuum melting, forging, machining, and heat treatment, all of which require advanced equipment and strict quality control measures. Additionally, shaping Nitinol into intricate medical device components, such as stents or guidewires, is challenging due to its hardness and elasticity, which increases machining difficulty and material wastage. This further adds to production costs.
Moreover, stringent regulatory standards for medical devices demand extensive testing, validation, and certification, increasing both time and financial investment for manufacturers. Smaller companies may find it difficult to bear these costs, limiting market entry and competition. As a result, the high cost of production and technical complexity restrict the broader adoption of Nitinol-based devices, particularly in price-sensitive healthcare markets, thereby acting as a key restraint on market growth.
| Key Pointers | Values |
| Report Focus | Global |
| Largest Region | North America |
| Fastest Growing Region | Asia Pacific |
| Base Year | 2024 |
| CAGR % (2027-2033) | 7.6% |
| Forecast Year | 2027-2033 |
| Historical Year | 2015-2024 |
| Market Size in 2025 | USD 4.86 Billion |
| Market Size in 2033 | USD 8.74 Billion |
| Countries Covered | U.S., Canada, Mexico, Germany, UK, France, Italy, Spain, Turkey, Israel, China, Japan, India, South Korea, Australia, SEA, Brazil, Chile, Argentina, Saudi Arabia, UAE, Qatar, South Africa, Rest of World |
| Key Driver & Challenges | Rising chronic diseases and aging population increase demand for minimally invasive procedures using Nitinol devices. High material and manufacturing costs limit adoption, especially in price-sensitive markets. |
| Segments Covered | By Product Type, By Application, By End-User |
Segmental Analysis
Based on Product Type, Nitinol-Based Medical Device market is segmented into Stents, Guidewires, Catheters, Retrieval Devices, Filters, Orthopedic Implants, Dental Devices, Neurovascular Devices, Others.
In the Global Nitinol-Based Medical Device Market, the stents segment clearly dominates among all product types, including guidewires, catheters, filters, orthopedic implants, and neurovascular devices.
Stents hold the largest market share primarily due to their extensive application in cardiovascular treatments. They are widely utilized to address conditions such as coronary artery disease, peripheral artery disease, and blocked arteries, which rank among the most prevalent health issues globally. The high incidence of cardiovascular disorders significantly fuels the demand for nitinol-based stents, establishing them as the leading revenue-generating segment.
Another critical factor contributing to their dominance is the unique properties of nitinol, including superelasticity and shape memory. These characteristics enable stents to expand within blood vessels and adapt to complex anatomical structures, ensuring improved clinical outcomes and long-term durability. As a result, they are highly favored by surgeons for minimally invasive procedures.
Moreover, ongoing technological advancements, such as self-expanding and drug-eluting stents, have further bolstered their adoption. In contrast to other segments like guidewires and catheters, which serve as essential but supportive tools, stents function as primary therapeutic devices that directly influence patient recovery and survival rates.
| Segments | Values |
| By Application | Cardiovascular Neurovascular Orthopedic Urology Gastroenterology Dentistry Others |
| By End-User | Hospitals & Clinics Ambulatory Surgical Centers (ASCs) Specialty Clinics Research & Academic Institutes Others |
Regional Landscape
In the context of regional analysis, the Nitinol-Based Medical Device market includes North America, Europe, Asia Pacific, South America, and the Middle East and Africa.
The market size of the North America was valued at USD 2.28 Billion in 2025 and is expected to reach USD 4.10 Billion by 2033, with a CAGR of 46.90% during the forecast period. The global Nitinol-based medical device market shows clear regional variation, with North America emerging as the dominant region, followed by Europe, while Asia-Pacific is the fastest-growing market.
North America leads the market, accounting for roughly 46.90% of global share, driven by its highly advanced healthcare infrastructure and rapid adoption of minimally invasive procedures. The region benefits from strong regulatory support, high healthcare spending, and the presence of major medical device manufacturers.
Additionally, a large patient pool suffering from cardiovascular and orthopedic disorders significantly boosts the demand for Nitinol-based devices such as stents and guidewires. Continuous innovation and early access to new technologies further strengthen its leadership position.
Europe holds the second-largest share, supported by a well-established medical device industry and increasing aging population. Countries such as Germany, France, and the UK contribute significantly due to strong clinical research and widespread use of minimally invasive treatments. However, stringent regulatory frameworks can sometimes slow product approvals compared to North America.
Asia-Pacific, although currently behind in total share, is the fastest-growing region. Rapid improvements in healthcare infrastructure, rising medical tourism, and increasing healthcare investments in countries like China and India are accelerating market expansion
Competitive Landscape
Some of the major companies operating within the Nitinol-Based Medical Device market are: B. Braun Melsungen AG, Stryker Corporation, Arthrex, Inc., Terumo Corporation, Zimmer Biomet Holdings, Boston Scientific Corporation, Cook Medical, Cordis and Others.
Table of Contents
1. Global Nitinol-Based Medical Device Market Introduction and Market Overview
1.1. Objectives of the Study
1.2. Global Nitinol-Based Medical Device Market Scope and Market Estimation
1.2.1. Global Nitinol-Based Medical Device Overall Market Size (US$ Billion), Market CAGR (%), Market forecast (2027 - 2033)
1.2.2. Global Nitinol-Based Medical Device Market Revenue Share (%) and Growth Rate (Y-o-Y) from 2019 - 2033
1.3. Market Segmentation
1.3.1. Product Type of Global Nitinol-Based Medical Device Market
1.3.2. Application of Global Nitinol-Based Medical Device Market
1.3.3. End-User of Global Nitinol-Based Medical Device Market
1.3.4. Region of Global Nitinol-Based Medical Device Market
2. Executive Summary
2.1. Demand Side Trends
2.2. Key Market Trends
2.3. Market Demand (US$ Billion) Analysis 2019 – 2024 and Forecast, 2027 - 2033
2.4. Demand and Opportunity Assessment
2.5. Market Dynamics
2.5.1. Drivers
2.5.2. Limitations
2.5.3. Opportunities
2.5.4. Impact Analysis of Drivers and Restraints
2.6. Cost Tear Down Analysis
2.7. Key Developments
2.8. Porter’s Five Forces Analysis
2.8.1. Bargaining Power of Suppliers
2.8.2. Bargaining Power of Buyers
2.8.3. Threat of Substitutes
2.8.4. Threat of New Entrants
2.8.5. Competitive Rivalry
2.9. PEST Analysis
2.9.1. Political Factors
2.9.2. Economic Factors
2.9.3. Social Factors
2.9.4. Technological Factors
3. Global Nitinol-Based Medical Device Market Estimates & Historical Trend Analysis (2019 - 2024)
4. Global Nitinol-Based Medical Device Market Estimates & Forecast Trend Analysis, by Product Type
4.1. Global Nitinol-Based Medical Device Market Revenue (US$ Billion) Estimates and Forecasts, Product Type, 2019 - 2033
4.1.1. Stents
4.1.2. Guidewires
4.1.3. Catheters
4.1.4. Retrieval Devices
4.1.5. Filters
4.1.6. Orthopedic Implants
4.1.7. Dental Devices
4.1.8. Neurovascular Devices
4.1.9. Others
5. Global Nitinol-Based Medical Device Market Estimates & Forecast Trend Analysis, by Application
5.1. Global Nitinol-Based Medical Device Market Revenue (US$ Billion) Estimates and Forecasts, Application, 2019 - 2033
5.1.1. Cardiovascular
5.1.2. Neurovascular
5.1.3. Orthopedic
5.1.4. Urology
5.1.5. Gastroenterology
5.1.6. Dentistry
5.1.7. Others
6. Global Nitinol-Based Medical Device Market Estimates & Forecast Trend Analysis, by End-User
6.1. Global Nitinol-Based Medical Device Market Revenue (US$ Billion) Estimates and Forecasts, End-User, 2019 - 2033
6.1.1. Hospitals & Clinics
6.1.2. Ambulatory Surgical Centers (ASCs)
6.1.3. Specialty Clinics
6.1.4. Research & Academic Institutes
6.1.5. Others
7. Global Nitinol-Based Medical Device Market Estimates & Forecast Trend Analysis, by Region
7.1. Global Nitinol-Based Medical Device Market Revenue (US$ Billion) Estimates and Forecasts, by Region, 2019 - 2033
7.1.1. North America
7.1.2. Europe
7.1.3. Asia Pacific
7.1.4. Middle East & Africa
7.1.5. South America
8. North America Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
8.1. North America Nitinol-Based Medical Device Market Assessments & Key Findings
8.1.1. North America Nitinol-Based Medical Device Market Introduction
8.1.2. North America Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
8.1.2.1. By Product Type
8.1.2.2. By Application
8.1.2.3. By End-User
8.1.2.4. By Country
8.1.2.4.1. The U.S.
8.1.2.4.1.1. By Product Type
8.1.2.4.1.2. By Application
8.1.2.4.1.3. By End-User
8.1.2.4.1.4. Top Companies Market Share in the U.S., 2019-2024
8.1.2.4.2. Canada
8.1.2.4.2.1. By Product Type
8.1.2.4.2.2. By Application
8.1.2.4.2.3. By End-User
8.1.2.4.2.4. Top Companies Market Share in Canada, 2019-2024
8.1.2.4.3. Mexico
8.1.2.4.3.1. By Product Type
8.1.2.4.3.2. By Application
8.1.2.4.3.3. By End-User
8.1.2.4.3.4. Top Companies Market Share in Mexico., 2019-2024
9. Western Europe Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
9.1. Western Europe Nitinol-Based Medical Device Market Assessments & Key Findings
9.1.1. Western Europe Nitinol-Based Medical Device Market Introduction
9.1.2. Western Europe Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
9.1.2.1. By Product Type
9.1.2.2. By Application
9.1.2.3. By End-User
9.1.2.4. By Country
9.1.2.4.1. Germany
9.1.2.4.1.1. By Product Type
9.1.2.4.1.2. By Application
9.1.2.4.1.3. By End-User
9.1.2.4.1.4. Top Companies Market Share in Germany, 2019-2024
9.1.2.4.2. Italy
9.1.2.4.2.1. By Product Type
9.1.2.4.2.2. By Application
9.1.2.4.2.3. By End-User
9.1.2.4.2.4. Top Companies Market Share in Italy, 2019-2024
9.1.2.4.3. U.K.
9.1.2.4.3.1. By Product Type
9.1.2.4.3.2. By Application
9.1.2.4.3.3. By End-User
9.1.2.4.3.4. Top Companies Market Share in U.K, 2019-2024
9.1.2.4.4. France
9.1.2.4.4.1. By Product Type
9.1.2.4.4.2. By Application
9.1.2.4.4.3. By End-User
9.1.2.4.4.4. Top Companies Market Share in France, 2019-2024
9.1.2.4.5. Spain
9.1.2.4.5.1. By Product Type
9.1.2.4.5.2. By Application
9.1.2.4.5.3. By End-User
9.1.2.4.5.4. Top Companies Market Share in Spain, 2019-2024
9.1.2.4.6. Benelux
9.1.2.4.6.1. By Product Type
9.1.2.4.6.2. By Application
9.1.2.4.6.3. By End-User
9.1.2.4.6.4. Top Companies Market Share in Benelux, 2019-2024
9.1.2.4.7. Nordics
9.1.2.4.7.1. By Product Type
9.1.2.4.7.2. By Application
9.1.2.4.7.3. By End-User
9.1.2.4.7.4. Top Companies Market Share in Nordics, 2019-2024
9.1.2.4.8. Rest of W. Europe
9.1.2.4.8.1. By Therapeutic Type of Therapy
9.1.2.4.8.2. By Application
9.1.2.4.8.3. By End-User
9.1.2.4.8.4. Top Companies Market Share in Rest of Western Europe, 2019-2024
10. Eastern Europe Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
10.1. Eastern Europe Nitinol-Based Medical Device Market Assessments & Key Findings
10.1.1. Eastern Europe Nitinol-Based Medical Device Market Introduction
10.1.2. Eastern Europe Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
10.1.2.1. By Product Type
10.1.2.2. By Application
10.1.2.3. By End-User
10.1.2.4. By Country
10.1.2.4.1. Russia
10.1.2.4.1.1. By Product Type
10.1.2.4.1.2. By Application
10.1.2.4.1.3. By End-User
10.1.2.4.1.4. Top Companies Market Share in Russia, 2019-2024
10.1.2.4.2. Hungary
10.1.2.4.2.1. By Product Type
10.1.2.4.2.2. By Application
10.1.2.4.2.3. By End-User
10.1.2.4.2.4. Top Companies Market Share in Hungary, 2019-2024
10.1.2.4.3. Poland
10.1.2.4.3.1. By Product Type
10.1.2.4.3.2. By Application
10.1.2.4.3.3. By End-User
10.1.2.4.3.4. Top Companies Market Share in Poland, 2019-2024
10.1.2.4.4. Balkan & Baltics
10.1.2.4.4.1. By Product Type
10.1.2.4.4.2. By Application
10.1.2.4.4.3. By End-User
10.1.2.4.4.4. Top Companies Market Share in Balkan and Baltics, 2019-2024
10.1.2.4.5. Rest of E. Europe
10.1.2.4.5.1. By Product Type
10.1.2.4.5.2. By Application
10.1.2.4.5.3. By End-User
10.1.2.4.5.4. Top Companies Market Share in Eastern Europe, 2019-2024
11. Asia Pacific Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
11.1. Asia Pacific Market Assessments & Key Findings
11.1.1. Asia Pacific Nitinol-Based Medical Device Market Introduction
11.1.2. Asia Pacific Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
11.1.2.1. By Product Type
11.1.2.2. By Application
11.1.2.3. By End-User
11.1.2.4. By Country
11.1.2.4.1. China
11.1.2.4.1.1. By Product Type
11.1.2.4.1.2. By Application
11.1.2.4.1.3. By End-User
11.1.2.4.1.4. Top Companies Market Share in China, 2019-2024
11.1.2.4.2. Japan
11.1.2.4.2.1. By Product Type
11.1.2.4.2.2. By Application
11.1.2.4.2.3. By End-User
11.1.2.4.2.4. Top Companies Market Share in Japan, 2019-2024
11.1.2.4.3. India
11.1.2.4.3.1. By Product Type
11.1.2.4.3.2. By Application
11.1.2.4.3.3. By End-User
11.1.2.4.3.4. Top Companies Market Share in India, 2019-2024
11.1.2.4.4. Australia & New Zealand
11.1.2.4.4.1. By Product Type
11.1.2.4.4.2. By Application
11.1.2.4.4.3. By End-User
11.1.2.4.4.4. Top Companies Market Share in Australia and New Zealand, 2019-2024
11.1.2.4.5. South Korea
11.1.2.4.5.1. By Product Type
11.1.2.4.5.2. By Application
11.1.2.4.5.3. By End-User
11.1.2.4.5.4. Top Companies Market Share in South Korea, 2019-2024
11.1.2.4.6. ASEAN
11.1.2.4.6.1. By Product Type
11.1.2.4.6.2. By Application
11.1.2.4.6.3. By End-User
11.1.2.4.6.4. Top Companies Market Share in ASEAN, 2019-2024
11.1.2.4.7. Rest of Asia Pacific
11.1.2.4.7.1. By Product Type
11.1.2.4.7.2. By Application
11.1.2.4.7.3. By End-User
11.1.2.4.7.4. Top Companies Market Share in Rest of Asia Pacific 2019-2024
12. Middle East & Africa Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
12.1. Middle East & Africa Market Assessments & Key Findings
12.1.1. Middle East & Africa Nitinol-Based Medical Device Market Introduction
12.1.2. Middle East & Africa Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
12.1.2.1. By Product Type
12.1.2.2. By Application
12.1.2.3. By End-User
12.1.2.4. By Country
12.1.2.4.1. UAE
12.1.2.4.1.1. By Product Type
12.1.2.4.1.2. By Application
12.1.2.4.1.3. By End-User
12.1.2.4.1.4. Top Companies Market Share in UAE, 2019-2024
12.1.2.4.2. Saudi Arabia
12.1.2.4.2.1. By Product Type
12.1.2.4.2.2. By Application
12.1.2.4.2.3. By End-User
12.1.2.4.2.4. Top Companies Market Share in Saudi Arabia, 2019-2024
12.1.2.4.3. Turkey
12.1.2.4.3.1. By Product Type
12.1.2.4.3.2. By Application
12.1.2.4.3.3. By End-User
12.1.2.4.3.4. Top Companies Market Share in Turkey, 2019-2024
12.1.2.4.4. South Africa
12.1.2.4.4.1. By Product Type
12.1.2.4.4.2. By Application
12.1.2.4.4.3. By End-User
12.1.2.4.4.4. Top Companies Market Share in South Africa, 2019-2024
12.1.2.4.5. Rest of MEA
12.1.2.4.5.1. By Product Type
12.1.2.4.5.2. By Application
12.1.2.4.5.3. By End-User
12.1.2.4.5.4. Top Companies Market Share in Rest of MEA, 2019-2024
13. Latin America Nitinol-Based Medical Device Market: Estimates & Forecast Trend Analysis
13.1. Latin America Market Assessments & Key Findings
13.1.1. Latin America Nitinol-Based Medical Device Market Introduction
13.1.2. Latin America Nitinol-Based Medical Device Market Size Estimates and Forecast (US$ Billion) (2019 - 2033)
13.1.2.1. By Product Type
13.1.2.2. By Application
13.1.2.3. By End-User
13.1.2.4. By Country
13.1.2.4.1. Brazil
13.1.2.4.1.1. By Product Type
13.1.2.4.1.2. By Application
13.1.2.4.1.3. By End-User
13.1.2.4.1.4. Top Companies Market Share in Brazil, 2019-2024
13.1.2.4.2. Argentina
13.1.2.4.2.1. By Product Type
13.1.2.4.2.2. By Application
13.1.2.4.2.3. By End-User
13.1.2.4.2.4. Top Companies Market Share in Argentina, 2019-2024
13.1.2.4.3. Colombia
13.1.2.4.3.1. By Product Type
13.1.2.4.3.2. By Application
13.1.2.4.3.3. By End-User
13.1.2.4.3.4. Top Companies Market Share in Colombia, 2019-2024
13.1.2.4.4. Rest of LATAM
13.1.2.4.4.1. By Product Type
13.1.2.4.4.2. By Application
13.1.2.4.4.3. By End-User
13.1.2.4.4.4. Top Companies Market Share in Rest of LATAM, 2019-2024
14. Country Wise Nitinol-Based Medical Device Market: Introduction
15. Competition Landscape
15.1. Global Nitinol-Based Medical Device Market Product Mapping
15.2. Global Nitinol-Based Medical Device Market Concentration Analysis, by Leading Players / Innovators / Emerging Players / New Entrants
15.3. Global Nitinol-Based Medical Device Market Tier Structure Analysis
15.4. Global Nitinol-Based Medical Device Market Concentration & Company Market Shares (%) Analysis, 2023
16. Company Profiles
16.1. B. Braun Melsungen AG
16.1.1. Company Overview & Key Stats
16.1.2. Revenue (USD Million), Sales (Units), and Gross Margin & Market Share, 2019-2024
16.1.3. Product Portfolio & Pricing Analysis
16.1.4. SWOT Analysis
16.1.5. Business Strategy & Recent Developments
16.2. Stryker Corporation
16.3. Arthrex, Inc.
16.4. Terumo Corporation
16.5. Zimmer Biomet Holdings
16.6. Boston Scientific Corporation
16.7. Cook Medical
16.8. Cordis
16.9. Others
17. Research Methodology
17.1. External Transportations / Databases
17.2. Internal Proprietary Database
17.3. Primary Research
17.4. Secondary Research
17.5. Assumptions
17.6. Limitations
17.7. Report FAQs
18. Research Findings & Conclusion
No of Tables: 250
No of Figures: 200